Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11233929 | 0.99 | MAPT (0.53) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11220984 | 0.87 | KMT2A (0.58) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL11226987 | 0.85 | KMT2A (0.44) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL9054497 | 0.81 | POLB (0.64) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7655781 | 0.79 | NSD2 (0.44) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11429114 | 0.74 | LCK (0.51) | LMNAPOLBGAA | |
| SCHEMBL19910569 | 0.74 | LMNA (0.62) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| Recainam SCHEMBL636093 | 0.74 | LMNA (0.51) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL11237210 | 0.73 | EPHX2 (0.40) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29409425 | 0.73 | ALDH1A1 (0.46) | MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348413-A | Anti-arrhythmic N-[3-alkylaminopropyl]-N'-phenylureas | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-07 | — | — | US | claimed |
| EP-0007184-B1 | UREA DERIVATIVES, PROCESSES FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-06-30 | — | — | EP | claimed |
| US-4224242-A | ANTI-ARRHYTHMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-09-23 | — | — | US | claimed |
| WO-1980000151-A1 | N-(3-ALKYLAMINOPROPYL)-N'-PHENYLUREAS | AMERICAN HOME PROD (US) | 1980-02-07 | — | — | WO | claimed |
| EP-0007184-A1 | Urea derivatives, processes for preparing them and compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-01-23 | — | — | EP | claimed |
| US-4348413-A | Anti-arrhythmic N-[3-alkylaminopropyl]-N'-phenylureas | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0007184-B1 | UREA DERIVATIVES, PROCESSES FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |
| US-4224242-A | ANTI-ARRHYTHMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| WO-1980000151-A1 | N-(3-ALKYLAMINOPROPYL)-N'-PHENYLUREAS | AMERICAN HOME PROD (US) | 1980-02-07 | — | — | WO | disclosed |
| EP-0007184-A1 | Urea derivatives, processes for preparing them and compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-01-23 | — | — | EP | disclosed |