Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771385 | 0.88 | POLB (0.69) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL5681508 | 0.88 | POLB (0.69) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL30516994 | 0.88 | POLB (0.72) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL1344307 | 0.88 | POLB (0.72) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL29372498 | 0.88 | POLB (0.72) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6577646 | 0.86 | NPC1 (0.72) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6430894 | 0.84 | MAPT (1.00) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL11242411 | 0.84 | NPC1 (0.65) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6629403 | 0.84 | NPC1 (0.61) | POLBKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL10967705 | 0.81 | MEN1 (0.64) | POLBKMT2AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334004-A | Light-sensitive diazotype material with 2-hydroxy-3-naphthoic acid amides having 6-sulfonic acid amide substitution | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| US-4321373-A | 2-Hydroxy-3-naphthoic acid amides | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-23 | — | — | US | disclosed |