Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455488 | 0.75 | SRD5A1 (0.46) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL9803355 | 0.71 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL1764564 | 0.69 | MEN1 (0.35) | HPGD | |
| SCHEMBL432048 | 0.69 | — | — | |
| SCHEMBL9802715 | 0.68 | HTT (0.36) | ALDH1A1 | |
| SCHEMBL4011609 | 0.68 | BRD4 (0.30) | — | |
| SCHEMBL58 | 0.68 | — | — | |
| SCHEMBL2201542 | 0.68 | — | — | |
| SCHEMBL10376304 | 0.68 | — | — | |
| SCHEMBL9803298 | 0.67 | CHRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329468-A | ADRENERGIC BLOCKING AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-11 | — | — | US | disclosed |
| US-4256890-A | ADRENERGIC BLOCKING AGENTS | OTSUKAPHARMACEUTICAL CO., LTD. (JP) | 1981-03-17 | — | — | US | disclosed |