Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10021627 | 0.75 | LMNA (0.54) | CYP2C19LMNA | |
| SCHEMBL28351185 | 0.75 | LMNA (0.54) | CYP2C19LMNA | |
| SCHEMBL32679459 | 0.74 | LMNA (0.59) | CYP2C19LMNACYP3A4CYP2C9GAA | |
| SCHEMBL3860656 | 0.72 | LMNA (0.47) | CYP2C19LMNACYP3A4CYP2C9GAA | |
| Chlorethoxyfos SCHEMBL117108 | 0.64 | CYP3A4 (0.35) | CYP2C19CYP3A4CYP2C9TP53TDP1 | |
| SCHEMBL10589277 | 0.64 | TP53 (0.39) | CYP2C19LMNACYP3A4CYP2C9GAA | |
| SCHEMBL8154040 | 0.63 | LMNA (0.39) | CYP2C19LMNA | |
| SCHEMBL8155311 | 0.63 | LMNA (0.39) | CYP2C19LMNA | |
| SCHEMBL8160584 | 0.63 | LMNA (0.39) | CYP2C19LMNA | |
| SCHEMBL7202958 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335117-A | 1-Hydroxy-2,2,2-trichloroethane-thionophosphonic acid dimethyl esters as insecticide | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |