Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327919 | 0.89 | GPR84 (0.57) | GPR84DHFRKCNH2ACP1NR1H3 | |
| SCHEMBL28827848 | 0.87 | GPR84 (0.58) | GPR84DHFRKCNH2ACP1NR1H3 | |
| SCHEMBL24383547 | 0.84 | HPGD (0.49) | ACP1NR1H3ADORA3ADORA2ALMNA | |
| SCHEMBL4251526 | 0.84 | GPR84 (0.55) | GPR84DHFRKCNH2ACP1NR1H3 | |
| SCHEMBL1959103 | 0.84 | GPR84 (0.55) | GPR84DHFRKCNH2ACP1NR1H3 | |
| SCHEMBL12732279 | 0.82 | GPR84 (0.51) | GPR84ACP1NR1H3HSD11B1ADORA3 | |
| SCHEMBL7523521 | 0.80 | LMNA (0.44) | ACP1NR1H3ADORA3ADORA2ALMNA | |
| SCHEMBL3835581 | 0.80 | GPR84 (0.51) | GPR84DHFRKCNH2ACP1NR1H3 | |
| SCHEMBL11417577 | 0.78 | KMT2A (0.44) | GPR84KCNH2LMNAKMT2A | |
| SCHEMBL11413687 | 0.78 | KMT2A (0.44) | GPR84KCNH2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051067-A1 | TRIAZINE SYNTHESIS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-05-12 | — | — | EP | disclosed |
| WO-1981003020-A1 | TRIAZINE SYNTHESIS | COMMW SCIENT IND RES ORG (AU) | 1981-10-29 | — | — | WO | disclosed |