SCHEMBL11237835

SCHEMBL11237835

O=C(CCc1ccc(Cl)cc1)CCn1ccnc1

nearest known ligand 0.78

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 3/20 0.58
CYP2A6 P11509 1/20 0.56
CYP19A1 P11511 1/20 0.56
CYP11B1 P15538 1/20 0.56
CYP11B2 P19099 1/20 0.56
CYP2B6 P20813 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11251579 0.87 CYP2A6 (0.58) TBXAS1CYP2A6CYP19A1CYP11B1CYP11B2
SCHEMBL406793 0.87 TBXAS1 (0.59) TBXAS1CYP2A6CYP19A1CYP11B1CYP11B2
SCHEMBL11256565 0.86 TBXAS1 (0.55) TBXAS1
SCHEMBL11279378 0.86 CYP19A1 (0.65) TBXAS1CYP19A1CYP11B1CYP11B2
SCHEMBL11253750 0.86 CYP19A1 (0.55) TBXAS1CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL408821 0.86 TBXAS1 (0.60) TBXAS1CYP2A6CYP19A1CYP11B1CYP11B2
SCHEMBL11240853 0.86 TBXAS1 (0.57) TBXAS1
Hydrochloric Acid SCHEMBL9996061 0.84 TBXAS1 (0.58) TBXAS1
SCHEMBL11281455 0.84 CYP11B1 (0.59) TBXAS1CYP11B1CYP11B2
SCHEMBL11240927 0.83 CYP19A1 (0.58) TBXAS1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359475-A SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS SYNTEX (U.S.A.) INC. (US) 1982-11-16 US disclosed
EP-0064244-A1 Spermicidal 1-bis(arylalkyl)alkylimidazoles SYNTEX (U.S.A.) INC. (US) 1982-11-10 EP disclosed
US-4321272-A Derivatives of substituted N-alkylimidazoles SYNTEX (U.S.A.) INC. (US) 1982-03-23 US disclosed
US-4123542-A FUNGICIDES, BACTERICIDES, ANTIPROTOZOAL AGENTS SYNTEX (U.S.A.) INC. (US) 1978-10-31 US disclosed