Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803260 | 0.88 | CYP19A1 (0.63) | CYP19A1F2RL1MEN1KMT2ATSHR | |
| SCHEMBL11240600 | 0.88 | CYP19A1 (0.60) | CYP19A1MEN1KMT2AATMTSHR | |
| Hydrochloric Acid SCHEMBL411003 | 0.87 | CYP19A1 (0.62) | CYP19A1F2RL1MEN1KMT2AATM | |
| Bromide SCHEMBL11242765 | 0.87 | CYP19A1 (0.62) | CYP19A1F2RL1MEN1KMT2ATSHR | |
| SCHEMBL11256565 | 0.85 | TBXAS1 (0.55) | TBXAS1 | |
| SCHEMBL11253750 | 0.85 | CYP19A1 (0.55) | CYP19A1TBXAS1 | |
| SCHEMBL11279378 | 0.83 | CYP19A1 (0.65) | CYP19A1TBXAS1 | |
| SCHEMBL11237835 | 0.83 | TBXAS1 (0.58) | CYP19A1TBXAS1 | |
| SCHEMBL11240853 | 0.82 | TBXAS1 (0.57) | TBXAS1 | |
| Hydrochloric Acid SCHEMBL9996061 | 0.81 | TBXAS1 (0.58) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |