SCHEMBL11237896

SCHEMBL11237896

CCCC1(CCC)COC(Cc2ccc(OC(C)(C)C)cc2)(Cn2ccnc2)OC1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HMOX1 P09601 4/20 0.41
TBXAS1 P24557 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11242048 0.92 TBXAS1 (0.41) HMOX1TBXAS1
SCHEMBL11243562 0.89 HMOX1 (0.43) HMOX1
SCHEMBL11247711 0.88 TBXAS1 (0.42) HMOX1TBXAS1
SCHEMBL11243141 0.87 HMOX1 (0.43) HMOX1
SCHEMBL11235741 0.86 HMOX1 (0.52) HMOX1TBXAS1
SCHEMBL11250274 0.85 CYP19A1 (0.46) HMOX1
SCHEMBL11236793 0.84 HMOX1 (0.55) HMOX1
SCHEMBL11238404 0.84 HMOX1 (0.47) HMOX1TBXAS1
SCHEMBL11238430 0.84 HMOX1 (0.44) HMOX1TBXAS1
SCHEMBL11241370 0.82 HMOX1 (0.44) HMOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0049565-A2 Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1982-04-14 EP disclosed
US-4321272-A Derivatives of substituted N-alkylimidazoles SYNTEX (U.S.A.) INC. (US) 1982-03-23 US disclosed