Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CDA | P32320 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223646 | 1.00 | KDM4E (0.46) | KDM4EPOLBGAACDAALDH1A1 | |
| SCHEMBL11685109 | 0.98 | KDM4E (0.43) | KDM4EPOLBGAACDAALDH1A1 | |
| SCHEMBL10493457 | 0.92 | KLK5 (0.42) | KDM4EPOLBGAACDAALDH1A1 | |
| SCHEMBL134244 | 0.83 | — | — | |
| SCHEMBL29904211 | 0.79 | KDM4E (0.44) | KDM4EPOLBGAACDAALDH1A1 | |
| SCHEMBL11308520 | 0.73 | HSD17B10 (0.41) | KDM4EPOLBGAACDAALDH1A1 | |
| SCHEMBL11689374 | 0.72 | GPR6 (0.38) | KDM4EPOLBGAAKLK5 | |
| SCHEMBL11729889 | 0.71 | KLK5 (0.42) | KDM4EPOLBGAAALDH1A1KLK5 | |
| SCHEMBL10630403 | 0.71 | LMNA (0.50) | KDM4EPOLBGAAALDH1A1MAPT | |
| SCHEMBL5281622 | 0.71 | LMNA (0.50) | KDM4EPOLBGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339381-A | 1,3-Alkylene-diazetidine-2,4-diones | THE UPJOHN COMPANY (US) | 1982-07-13 | — | — | US | disclosed |