SCHEMBL5281622

SCHEMBL5281622

O=C(Cl)N1CCCCCC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
MITF O75030 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
THRB P10828 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
ALDH1A1 P00352 3/20 0.37
TP53 P04637 2/20 0.37
HSD17B10 Q99714 2/20 0.37
STAT6 P42226 1/20 0.37
MDM2 Q00987 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10630403 1.00 LMNA (0.50) LMNAMITFSMN1; SMN2KMT2AL3MBTL1
SCHEMBL11189347 0.98 LMNA (0.52) LMNAMITFSMN1; SMN2KMT2AL3MBTL1
SCHEMBL3404151 0.91
SCHEMBL8379227 0.82 LMNA (0.54) LMNAMITFSMN1; SMN2KMT2AL3MBTL1
SCHEMBL131845 0.82 LMNA (0.54) LMNAMITFSMN1; SMN2KMT2AL3MBTL1
SCHEMBL5181091 0.82 LMNA (0.54) LMNAMITFSMN1; SMN2KMT2AL3MBTL1
SCHEMBL4059818 0.80 LMNA (0.52) LMNAMITFSMN1; SMN2KMT2AL3MBTL1
SCHEMBL4062492 0.80 LMNA (0.52) LMNAMITFSMN1; SMN2KMT2AL3MBTL1
SCHEMBL7687599 0.79 LMNA (0.56) LMNAMITFSMN1; SMN2KMT2AKDM4E
SCHEMBL8379280 0.78 SMN1; SMN2 (0.50) LMNAMITFSMN1; SMN2KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002062754-A1 METHOD FOR PRODUCING N,N'-CARBONYLBIS-$G(e)-CAPROLACTAM BASF AKTIENGESELLSCHAFT (DE) 2002-08-15 WO claimed
EP-0147051-B1 PRODUCTION OF POLYETHER-POLYAMIDE BLOCK COPOLYMERS AND PREPOLYMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-01-15 EP claimed
US-4792603-A REACTING POLYOXYALKYLENE WITH CHLOROCARBONYL LACTAM SUMITOMO CHEMICAL CO., LTD. (JP) 1988-12-20 US claimed
EP-0156079-A2 Polyether polyoxyalkylene prepolymers and block copolymers made therefrom SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-02 EP claimed
EP-0147051-A2 Production of polyether-polyamide block copolymers and prepolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-07-03 EP claimed
JP-61004729-A None JP disclosed
JP-60250029-A None JP disclosed
JP-60137930-A None JP disclosed
JP-60112825-A None JP disclosed
JP-60179423-A None JP disclosed
WO-2007006491-A2 PRODUCTION OF ORGANOSILICON COMPOUNDS COMPRISING A MASKED ISOCYANATE GROUP WACKER CHEMIE AG (DE) 2007-01-18 WO disclosed
WO-2002062754-A1 METHOD FOR PRODUCING N,N'-CARBONYLBIS-$G(e)-CAPROLACTAM BASF AKTIENGESELLSCHAFT (DE) 2002-08-15 WO disclosed
US-4016282-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
US-3980792-A EFFECTIVE AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE INFECTIONS BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3978223-A UREIDOACETAMIDO-PENICILLINS FOR TREATING BACTERIAL INFECTIONS BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed
US-3974140-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3959258-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3939149-A BACTERICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed
US-3936442-A ANTIBIOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US disclosed
US-3933795-A Ureidoacetamido-penicillins Konig, Hans-Bodo (DT) 1976-01-20 US disclosed