Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.73 |
| ▸ | DRD1 | P21728 | 6/20 | 0.72 |
| ▸ | HTR2A | P28223 | 2/20 | 0.72 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.72 |
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | HTR7 | P34969 | 1/20 | 0.72 |
| ▸ | HTR1A | P08908 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | RAD52 | P43351 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32690196 | 1.00 | DRD2 (0.73) | DRD2DRD1HTR2APNPLA2HTR2C | |
| SCHEMBL17291139 | 0.85 | DRD2 (0.59) | DRD2DRD1HTR2APNPLA2HTR2C | |
| (+/-)-Nuciferine SCHEMBL634777 | 0.84 | HTR2A (1.00) | DRD2DRD1HTR2APNPLA2HTR2C | |
| Nuciferine SCHEMBL29521272 | 0.84 | HTR2A (1.00) | DRD2DRD1HTR2APNPLA2HTR2C | |
| Nuciferine SCHEMBL20544868 | 0.84 | HTR2A (1.00) | DRD2DRD1HTR2APNPLA2HTR2C | |
| SCHEMBL2556809 | 0.83 | DRD2 (0.57) | DRD2DRD1HTR2APNPLA2HTR2C | |
| Hydrochloric Acid SCHEMBL9468977 | 0.83 | DRD2 (0.97) | DRD2DRD1HTR7HTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL9468976 | 0.83 | DRD2 (0.97) | DRD2DRD1HTR7HTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL9468499 | 0.83 | DRD2 (0.97) | DRD2DRD1HTR7HTR1ACYP1A2 | |
| SCHEMBL14494966 | 0.83 | DRD2 (1.00) | DRD2DRD1HTR1ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309542-A | WITH A TRIMETHYLPHENYLAMMONIUM BASE | WARNER-LAMBERT COMPANY (US) | 1982-01-05 | — | — | US | disclosed |