Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 1.00 |
| ▸ | DRD1 | P21728 | 9/20 | 1.00 |
| ▸ | DRD2 | P14416 | 8/20 | 1.00 |
| ▸ | HTR7 | P34969 | 8/20 | 1.00 |
| ▸ | HTR2C | P28335 | 8/20 | 1.00 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 8/20 | 0.80 |
| ▸ | HTR2B | P41595 | 8/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.80 |
| ▸ | TDP2 | O95551 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | CASP3 | P42574 | 2/20 | 0.80 |
| ▸ | RAD52 | P43351 | 2/20 | 0.80 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.80 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.80 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.80 |
| ▸ | APAF1 | O14727 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nuciferine SCHEMBL20544868 | 1.00 | HTR2A (1.00) | HTR2ADRD1DRD2HTR7HTR2C | |
| Nuciferine SCHEMBL29521272 | 1.00 | HTR2A (1.00) | HTR2ADRD1DRD2HTR7HTR2C | |
| (+/-)-Nuciferine SCHEMBL11710956 | 0.99 | HTR2A (0.98) | HTR2ADRD1DRD2HTR7HTR2C | |
| Glaucine SCHEMBL30213021 | 0.89 | HTR2A (1.00) | HTR2ADRD1DRD2HTR7HTR2C | |
| Glaucine SCHEMBL146441 | 0.89 | HTR2A (1.00) | HTR2ADRD1DRD2HTR7HTR2C | |
| Glaucine SCHEMBL29735463 | 0.89 | HTR2A (1.00) | HTR2ADRD1DRD2HTR7HTR2C | |
| Glaucine SCHEMBL3040938 | 0.89 | HTR2A (1.00) | HTR2ADRD1DRD2HTR7HTR2C | |
| SCHEMBL11710907 | 0.88 | HTR2A (0.79) | HTR2ADRD1DRD2HTR7HTR2C | |
| Glaucine SCHEMBL11249152 | 0.88 | KDM4E (1.00) | HTR2ADRD1DRD2HTR7HTR2C | |
| Glaucine SCHEMBL11166124 | 0.88 | HTR2A (0.97) | HTR2ADRD1DRD2HTR7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3061 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122075490-A | Application of liensinine in preparation of medicine for treating polycystic ovary syndrome | — | 2026-05-26 | — | — | CN | claimed |
| CN-122059939-A | Mountain lotus leaf essence sulfonamide derivative, and preparation method and application thereof | 南通大学 | 2026-05-19 | — | — | CN | claimed |
| CN-119371356-B | Nuciferine derivative, and preparation method and application thereof | 云南中医药大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122056926-A | Probiotic composition containing melatonin and application of composition in sleep | 南京北极光生物科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122059940-A | Mountain lotus leaf essence urea derivative and preparation method and application thereof | 南通大学 | 2026-05-19 | — | — | CN | claimed |
| CN-121153606-B | Laboratory mouse raising control system applied to nuciferine research | 湘潭亮鑫农业综合开发有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-121577798-A | Method for simultaneously measuring contents of 5 ingredients in medicinal and edible beverage and application thereof | 河南中医药大学第一附属医院 | 2026-02-27 | — | — | CN | claimed |
| CN-121574897-A | Drug lotus cell suspension factory system and method for directionally producing high-activity component based on health target point | 湖北中莲湿地研究院有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-120189414-A | Application of nuciferine or pharmaceutically acceptable salt thereof in preparation of medicines for preventing and/or treating myocardial hypertrophy | 武汉大学人民医院（湖北省人民医院） | 2025-06-24 | — | — | CN | claimed |
| US-20250195505-A1 | USE OF DEXTROMETHORPHAN IN COMBINATION WITH CYP2D6 AND CYP3A4 ENZYME INHIBITORS FOR THE TREATMENT OF PAIN | BIOBINA LLC | 2025-06-19 | — | — | US | claimed |
| CN-101139320-A | Method for separating nuciferine and lotus leaf flavone from lotus leaf | UNIV FUZHOU (CN) | 2008-03-12 | — | — | CN | claimed |
| CN-101134066-A | Technique of preparing lotus nut dropping pills for treating quick type arrhythmia | CHINA MEDICAL SCIENCE ACADEMY (CN) | 2008-03-05 | — | — | CN | claimed |
| CN-101085041-A | Total alkaloid of lotus leaves extraction and its preparation method | RENBING SHI (CN) | 2007-12-12 | — | — | CN | claimed |
| WO-2007110637-A1 | METHOD FOR EXTRACTING TARGET ALKALOID USING AN IONIC LIQUID AS EXTRACTING SOLVENT | BIONIQS LIMITED (GB) | 2007-10-04 | — | — | WO | claimed |
| CN-1981840-A | Chinese-medicinal composition with anti-inflammatory and hemostasis functions and its production | FAN CUISHENG (CN) | 2007-06-20 | — | — | CN | claimed |
| CN-1850837-A | 9-(1,3-benzo dioxolyl-5_)-4-(beta-D-glucopyranosyloxy)-6,7-dimethoxy naphthale [2,3-C] furna-1(3II] ketone, and its preparing method and medicinal composition containing same | TIAN BING (CN) | 2006-10-25 | — | — | CN | claimed |
| CN-1689615-A | Bleeding arresting Chinese medicinal composition and its preparation method | FAN CUISHENG (CN) | 2005-11-02 | — | — | CN | claimed |
| CN-1249905-A | Coffee-like blood pressure-reducing health tea | ZHANG WEI (CN) | 2000-04-12 | — | — | CN | claimed |
| CN-1166337-A | Weight-reducing tea | FANG DONGSHENG (CN) | 1997-12-03 | — | — | CN | claimed |
| CN-1154948-A | Physiological water for drinking and prepn. method thereof | CHENG YINGBO (CN) | 1997-07-23 | — | — | CN | claimed |