SCHEMBL11238481

SCHEMBL11238481

CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)[C]=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.39
DPP4 P27487 14/20 0.39
DPP8 Q6V1X1 9/20 0.39
DPP9 Q86TI2 9/20 0.39
MME P08473 1/20 0.36
ACE P12821 1/20 0.36
CPA1 P15085 1/20 0.36
ACE2 Q9BYF1 1/20 0.36
DPP7 Q9UHL4 8/20 0.35
FAP Q12884 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2196455 0.84 ENPEP (0.42) DPP4DPP8DPP9
SCHEMBL4264859 0.84 DPP4 (0.38) TERTDPP4DPP8DPP9MME
SCHEMBL27952599 0.84 DPP4 (0.38) TERTDPP4DPP8DPP9MME
SCHEMBL4264858 0.84 DPP4 (0.38) TERTDPP4DPP8DPP9MME
SCHEMBL11762941 0.82 DPP4 (0.37) TERTDPP4DPP8DPP9MME
SCHEMBL11762950 0.82 DPP4 (0.37) TERTDPP4DPP8DPP9MME
SCHEMBL8037061 0.81 DPP4 (0.37) TERTDPP4DPP8DPP9MME
SCHEMBL15700570 0.80 ALDH1A1 (0.46) TERTDPP4DPP8DPP9MME
SCHEMBL1034776 0.80 DPP4 (0.53) DPP4DPP8DPP9DPP7FAP
SCHEMBL1034774 0.80 DPP4 (0.53) DPP4DPP8DPP9DPP7FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4314936-A BY MEASUREM,ENT OF FLUORESENCE YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1982-02-09 US claimed
US-4314936-A BY MEASUREM,ENT OF FLUORESENCE YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1982-02-09 US disclosed