SCHEMBL11238833

SCHEMBL11238833

CC(C)(C)/C(Cn1cnnc1)=N\O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
CYP19A1 P11511 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11238843 1.00 ESR1 (0.31) ESR1CYP19A1ESR2
SCHEMBL11234253 0.77 ALDH1A1 (0.47) ESR1CYP19A1ESR2
SCHEMBL11234254 0.77 ALDH1A1 (0.47) ESR1CYP19A1ESR2
SCHEMBL11238237 0.71 CSF1R (0.31)
SCHEMBL11238229 0.71 CSF1R (0.31)
SCHEMBL10846758 0.70 TSHR (0.41) ESR1CYP19A1ESR2
SCHEMBL11238618 0.69 FDPS (0.38) CYP19A1
SCHEMBL11238616 0.69 FDPS (0.38) CYP19A1
SCHEMBL11246160 0.69 CYP19A1 (0.36) CYP19A1
SCHEMBL11246157 0.69 CYP19A1 (0.36) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed
EP-0005780-A1 N,N'-asymmetrically substituted thio-bis-amines, process for their preparation and their use as insecticides, acaricides and nematocides BAYER AG (DE) 1979-12-12 EP disclosed