Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246997 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL11247997 | 0.89 | MAPT (0.39) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL11252871 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL11253832 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL11242215 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL11248643 | 0.77 | PGR (0.41) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL11252803 | 0.77 | SERPINA6 (0.46) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL11248480 | 0.71 | PGR (0.59) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL8915251 | 0.70 | SERPINA6 (0.71) | ALDH1A1MAPTLMNACYP3A4MEN1 | |
| SCHEMBL11096491 | 0.69 | SERPINA6 (0.36) | ALDH1A1MAPTLMNACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012641-B1 | SUBSTITUTED-19-NOR-PREGN-4-ENE-3,20-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1982-05-12 | — | — | EP | disclosed |