Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 3/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238681 | 0.95 | HMOX1 (0.44) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11252757 | 0.91 | CYP11B1 (0.51) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11249818 | 0.89 | CYP11B1 (0.39) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11239249 | 0.87 | HMOX1 (0.41) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11246026 | 0.87 | HMOX1 (0.58) | HMOX1 | |
| SCHEMBL11238324 | 0.87 | CYP11B1 (0.55) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11240041 | 0.87 | CYP11B1 (0.37) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11243127 | 0.85 | CYP11B1 (0.49) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11246392 | 0.85 | HMOX1 (0.38) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11233061 | 0.83 | HMOX1 (0.56) | HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |