Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238716 | 0.94 | MAPT (0.55) | MAPTSPHK1THRATHRBS1PR1 | |
| SCHEMBL11229504 | 0.94 | MAPT (0.55) | MAPTSPHK1THRATHRBS1PR1 | |
| SCHEMBL11244214 | 0.94 | MAPT (0.55) | MAPTSPHK1THRATHRBS1PR1 | |
| SCHEMBL11243750 | 0.89 | KDM4E (0.59) | ADRB2ADRB1ADRB3SPHK1SPHK2 | |
| SCHEMBL11225752 | 0.89 | KDM4E (0.59) | ADRB2ADRB1ADRB3SPHK1SPHK2 | |
| SCHEMBL11241552 | 0.89 | KDM4E (0.59) | ADRB2ADRB1ADRB3SPHK1SPHK2 | |
| SCHEMBL11240378 | 0.87 | CYP4Z1 (0.52) | SPHK1THRATHRBS1PR1 | |
| SCHEMBL11237134 | 0.83 | KDM4E (0.56) | ADRB2ADRB1ADRB3SPHK1KDM4E | |
| SCHEMBL11238302 | 0.83 | KDM4E (0.56) | ADRB2ADRB1ADRB3SPHK1KDM4E | |
| SCHEMBL11237441 | 0.83 | KDM4E (0.56) | ADRB2ADRB1ADRB3SPHK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |