Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 4/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225752 | 1.00 | KDM4E (0.59) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11243750 | 1.00 | KDM4E (0.59) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11238302 | 0.94 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11237441 | 0.94 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11237134 | 0.94 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11303411 | 0.92 | DGKA (0.64) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11239282 | 0.89 | MAPT (0.57) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11304340 | 0.86 | DGKA (0.61) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL11240378 | 0.85 | CYP4Z1 (0.52) | FAAHSPHK1 | |
| SCHEMBL11229504 | 0.83 | MAPT (0.55) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |