Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241233 | 0.87 | HTT (0.35) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL11237305 | 0.86 | S100B (0.34) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL11239691 | 0.86 | ALDH1A1 (0.38) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL11379713 | 0.86 | ALDH1A1 (0.40) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL11232619 | 0.86 | FFAR4 (0.35) | MAPTRPS6KA2HTTLMNASMN1; SMN2 | |
| SCHEMBL11364534 | 0.85 | MAPT (0.41) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL9254824 | 0.85 | ALDH1A1 (0.44) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL9186491 | 0.84 | ALDH1A1 (0.50) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL11441219 | 0.84 | RPS6KA2 (0.41) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL11243023 | 0.84 | GFER (0.37) | HSD17B10ALDH1A1CYP3A4HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |