Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA7 | P43166 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | CA5A | P35218 | 2/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239625 | 1.00 | LMNA (0.60) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL11246091 | 0.87 | FAAH (0.56) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL11246098 | 0.87 | FAAH (0.56) | LMNAAKR1B10AKR1B1CA12CA7 | |
| SCHEMBL11229892 | 0.86 | CA12 (0.57) | CA12CA7CA9CA14TTR | |
| SCHEMBL11229891 | 0.86 | CA12 (0.57) | CA12CA7CA9CA14TTR | |
| SCHEMBL11229500 | 0.85 | ZDHHC2 (0.60) | EGFRHDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL11239735 | 0.85 | EGFR (0.48) | LMNACA12CA7CA9CA14 | |
| SCHEMBL11229503 | 0.85 | ZDHHC2 (0.60) | EGFRHDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL11239738 | 0.85 | EGFR (0.48) | LMNACA12CA7CA9CA14 | |
| SCHEMBL11239647 | 0.84 | EGFR (0.44) | LMNAAKR1B10AKR1B1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |