SCHEMBL11239660

SCHEMBL11239660

N#Cc1cnc(NC=O)s1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDR P35968 12/20 0.49
FFAR2 O15552 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22750811 0.76
SCHEMBL12562416 0.76
SCHEMBL8993668 0.73 MYC (0.51)
SCHEMBL2690664 0.73 FFAR2 (0.53) KDRFFAR2
SCHEMBL212741 0.72
SCHEMBL31567875 0.72
SCHEMBL27761438 0.72
SCHEMBL4394535 0.69 FFAR2 (0.49) KDRFFAR2
SCHEMBL6330170 0.69 KDR (0.65) KDR
SCHEMBL22522895 0.68 CNR2 (0.36) FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4324899-A 2-Amino-5-cyanothiazoles and their preparation EASTMAN KODAK COMPANY (US) 1982-04-13 US claimed
US-4324899-A 2-Amino-5-cyanothiazoles and their preparation EASTMAN KODAK COMPANY (US) 1982-04-13 US disclosed
US-4324899-A 2-Amino-5-cyanothiazoles and their preparation EASTMAN KODAK COMPANY (US) 1982-04-13 US disclosed