SCHEMBL8993668

SCHEMBL8993668

N#CSc1cnc(NC=O)s1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MYC P01106 2/20 0.51
WDR5 P61964 2/20 0.51
CDK1 P06493 1/20 0.30
CDK4 P11802 1/20 0.30
CCNE1 P24864 1/20 0.30
CDK2 P24941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL998733 0.76 MYC (0.51) MYCWDR5CDK1CDK4CCNE1
SCHEMBL5215449 0.76 CCNE1 (0.55) MYCWDR5CDK1CDK4CCNE1
SCHEMBL8993621 0.75 MYC (0.50) MYCWDR5CDK1CDK4CCNE1
SCHEMBL11239660 0.73 KDR (0.49)
SCHEMBL2067788 0.69 KDR (0.63) MYCWDR5CDK1CDK4CCNE1
SCHEMBL1133564 0.68 SMN1; SMN2 (0.42) MYCWDR5CDK1CDK4CCNE1
SCHEMBL14394596 0.68
SCHEMBL212741 0.68
SCHEMBL737078 0.68
SCHEMBL27761438 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7069814-A None JP disclosed
US-5491157-A USING 2-AMINO-5-THIAZOLYL THIOCYANATE EASTMAN KODAK COMPANY (US) 1996-02-13 US disclosed
JP-H0769814-A METHOD AND COMPOSITION FOR PREVENTION, CONTROL AND AMELIORATION OF SOILBORNE BACTERIA AND FUNGI AND DISEASE CAUSED THEREBY AMERICAN CYANAMID CO 1995-03-14 JP disclosed
EP-0625307-A1 Method and composition for the control of soilborne fungi and prevention of diseases caused by them AMERICAN CYANAMID COMPANY (US) 1994-11-23 EP disclosed
EP-0082498-B1 BETA-LACTAM COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-11-02 EP disclosed
EP-0082498-A2 Beta-lactam compounds and process for the preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1983-06-29 EP disclosed