SCHEMBL11239664

SCHEMBL11239664

O=C(O)CCc1ccccc1NCc1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 13/20 0.61
FFAR4 Q5NUL3 5/20 0.52
L3MBTL1 Q9Y468 2/20 0.49
MAPT P10636 1/20 0.49
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.48
PLAAT3 P53816 1/20 0.48
PLAAT5 Q96KN8 1/20 0.48
PLAAT2 Q9NWW9 1/20 0.48
PLAAT4 Q9UL19 1/20 0.48
POLB P06746 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11252360 0.85 MAPT (0.47) FFAR1L3MBTL1MAPTALDH1A1LMNA
SCHEMBL11243171 0.82 MAPT (0.54) L3MBTL1MAPTALDH1A1HPGD
SCHEMBL7867033 0.79 MAPT (0.53) L3MBTL1MAPTALDH1A1LMNAHPGD
SCHEMBL11633504 0.77 FFAR1 (0.51) FFAR1FFAR4
SCHEMBL10572269 0.76 MAPT (0.48) L3MBTL1MAPTALDH1A1LMNAPOLB
SCHEMBL14399036 0.76 ALDH1A1 (0.74) L3MBTL1MAPTALDH1A1LMNAPOLB
SCHEMBL11239667 0.76 FFAR1 (1.00) FFAR1FFAR4
SCHEMBL12263035 0.76 MAPT (0.64) L3MBTL1MAPTALDH1A1HPGDHSD17B10
SCHEMBL11217423 0.73 HSD17B10 (0.55) FFAR1FFAR4L3MBTL1ALDH1A1POLB
SCHEMBL9044958 0.73 MEN1 (0.67) L3MBTL1MAPTALDH1A1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4362892-A ARALKYLANILINES, ANTICHOLESTEROL AGENTS BEECHAM GROUP LIMITED (GB) 1982-12-07 US disclosed
US-4206145-A ALKANOYL-SUBSTITUTED ARALKYLAMINES BEECHAM GROUP LIMITED (GB) 1980-06-03 US disclosed