Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27458277 | 0.88 | KEAP1 (0.63) | FFAR1FFAR4KEAP1PLA2G4AHTR2A | |
| SCHEMBL9173189 | 0.83 | FFAR1 (0.53) | FFAR1FFAR4KEAP1PLA2G4AHTR2A | |
| SCHEMBL59198 | 0.80 | KEAP1 (0.65) | FFAR1FFAR4KEAP1 | |
| SCHEMBL9179978 | 0.78 | CA1 (0.46) | FFAR1KEAP1 | |
| SCHEMBL349314 | 0.78 | FFAR1 (0.71) | FFAR1FFAR4KEAP1PDPK1MEN1 | |
| SCHEMBL11631691 | 0.78 | NR4A1 (0.58) | FFAR1FFAR4 | |
| SCHEMBL11239664 | 0.77 | FFAR1 (0.61) | FFAR1FFAR4 | |
| SCHEMBL9785808 | 0.77 | FFAR1 (0.55) | FFAR1KEAP1PLA2G4A | |
| SCHEMBL11635445 | 0.77 | KMT2A (0.49) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11045221 | 0.76 | FFAR1 (0.69) | FFAR1FFAR4KEAP1PDPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111997-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY | TAKEDA CHEMICAL COMPANY, LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-4007225-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-02-08 | — | — | US | disclosed |
| US-3953500-A | ANTIPYRETICS, ANALGESICS, ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-27 | — | — | US | disclosed |