Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11587450 | 0.87 | S1PR1 (0.57) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL846128 | 0.85 | ALDH1A1 (0.57) | FFAR1FFAR4S1PR1ALDH1A1LMNA | |
| SCHEMBL11587329 | 0.85 | ALDH1A1 (0.56) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL7625204 | 0.84 | THRA (0.60) | FFAR1FFAR4THRATHRBS1PR1 | |
| SCHEMBL11226774 | 0.83 | CYP4F2 (0.55) | THRATHRB | |
| SCHEMBL25466683 | 0.82 | KCNH2 (0.54) | THRATHRBALDH1A1LMNA | |
| SCHEMBL25466694 | 0.82 | KCNH2 (0.54) | THRATHRBALDH1A1LMNA | |
| SCHEMBL21523346 | 0.82 | KCNH2 (0.54) | THRATHRBALDH1A1LMNA | |
| SCHEMBL25466682 | 0.82 | KCNH2 (0.54) | THRATHRBALDH1A1LMNA | |
| SCHEMBL22321072 | 0.82 | KCNH2 (0.54) | THRATHRBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |