Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 9/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661661 | 0.98 | TRPM8 (0.48) | TRPM8LPAR3LPAR2TSHRFAAH | |
| SCHEMBL646902 | 0.93 | TRPM8 (0.48) | TRPM8LPAR3LPAR2TSHRFAAH | |
| SCHEMBL9681978 | 0.79 | LPAR3 (0.52) | TRPM8LPAR3LPAR2FAAH | |
| SCHEMBL27722655 | 0.79 | LPAR3 (0.52) | TRPM8LPAR3LPAR2FAAH | |
| SCHEMBL9386853 | 0.79 | LPAR3 (0.54) | TRPM8LPAR3LPAR2TSHR | |
| SCHEMBL31590811 | 0.79 | LPAR3 (0.54) | TRPM8LPAR3LPAR2TSHR | |
| SCHEMBL31590554 | 0.79 | LPAR3 (0.54) | TRPM8LPAR3LPAR2TSHR | |
| SCHEMBL31590283 | 0.79 | LPAR3 (0.54) | TRPM8LPAR3LPAR2TSHR | |
| SCHEMBL25323220 | 0.78 | LPAR3 (0.62) | TRPM8LPAR3LPAR2TSHRFAAH | |
| SCHEMBL13478275 | 0.78 | LPAR3 (0.62) | TRPM8LPAR3LPAR2TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365094-A | REACTION OF HALOMETHYL COMPOUND OR POLYMER WITH SECONDARY PHOSPHINE OXIDE | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1982-12-21 | — | — | US | disclosed |