SCHEMBL11239835

SCHEMBL11239835

OCc1cc2c(o1)CCCC2

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3548213 0.96 KDM4E (0.33) KDM4EPOLB
SCHEMBL13318359 0.79
SCHEMBL28682347 0.73 TLR8 (0.36) KDM4E
SCHEMBL28693007 0.71 PPARG (0.43)
SCHEMBL10160746 0.67 TSHR (0.33) TDP1
SCHEMBL16320316 0.62 CDC25B (0.30)
SCHEMBL29615910 0.60 CA2 (0.39) KDM4E
SCHEMBL28588903 0.60 NPC1 (0.40) KDM4ECYP1A2CYP3A4CYP2C19POLB
SCHEMBL3544207 0.58 CYP2A6 (0.34) POLB
SCHEMBL13424016 0.58 ALOX15 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4327109-A INSECTICIDES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1982-04-27 US disclosed
US-4229469-A Insecticidal alkadienylcyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1980-10-21 US disclosed
US-3998868-A INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-12-21 US disclosed
US-3954814-A INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-04 US disclosed