Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250082 | 0.78 | METAP1 (0.37) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL11242751 | 0.76 | METAP1 (0.35) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL20286520 | 0.73 | EPHX1 (0.38) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL19193858 | 0.69 | MMP2 (0.43) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL6704942 | 0.69 | EPHX1 (0.43) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL19866252 | 0.69 | EPHX1 (0.43) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL4813728 | 0.68 | EPHX1 (0.48) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL6242702 | 0.68 | EPHX1 (0.46) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL11773858 | 0.68 | MMP2 (0.46) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL20572951 | 0.67 | MMP2 (0.44) | MMP2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361577-A | ANTIULCER AND LUTEOLYTIC AGENTS | CARLO ERBA - S.P.A. (IT) | 1982-11-30 | — | — | US | disclosed |
| US-4169145-A | ANTIULCER AGENTS, LUTEOLYTIC ABORTIFACIENTS, OXYTOCICS | CARLO ERBA S.P.A. (IT) | 1979-09-25 | — | — | US | disclosed |
| US-4035415-A | GASTROINTESTINAL DISORDERS | CARLO ERBA, S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |