Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12868350 | 0.83 | EPHX1 (0.52) | EPHX1ALDH1A1CA12CA1CA2 | |
| SCHEMBL13301086 | 0.70 | EPHX1 (0.58) | EPHX1ALDH1A1CA12CA1CA2 | |
| SCHEMBL8462548 | 0.70 | EPHX1 (0.41) | EPHX1ALDH1A1CA12CA1CA2 | |
| SCHEMBL13911916 | 0.69 | EPHX1 (0.47) | EPHX1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11197502 | 0.69 | EPHX1 (0.64) | EPHX1ALDH1A1CA12CA1CA2 | |
| SCHEMBL7786725 | 0.69 | EPHX1 (0.56) | EPHX1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11239875 | 0.68 | MMP2 (0.44) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL12744562 | 0.68 | EPHX1 (0.40) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL17316191 | 0.67 | EPHX1 (0.61) | EPHX1ALDH1A1EPHX2NPC1RAB9A | |
| SCHEMBL66996 | 0.67 | EPHX1 (0.61) | EPHX1ALDH1A1EPHX2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368509-B2 | Functional norbornenes and polymeric derivatives and fabrication thereof | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2008-05-06 | — | — | US | disclosed |
| US-20070167580-A1 | Functional norbornenes and polymeric derivatives and fabrication thereof | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-07-19 | — | — | US | disclosed |
| US-7205359-B2 | Functional norbornenes as initiators for radical polymerization, their polymeric derivatives and a process for producing the same | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2007-04-17 | — | — | US | disclosed |
| US-20050182220-A1 | Novel functional norbornenes as initiators for radical polymerization, their polymeric derivatives and a process for producing the same | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOY (TW) | 2005-08-18 | — | — | US | disclosed |