Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL409075 | 0.97 | TDP1 (0.43) | TDP1POLBAPEX1HTTTSHR | |
| Styrene SCHEMBL9305623 | 0.97 | TDP1 (0.43) | TDP1POLBAPEX1HTTTSHR | |
| Styrene SCHEMBL28447649 | 0.94 | TDP1 (0.41) | TDP1POLBAPEX1HTTTSHR | |
| Styrene SCHEMBL28571582 | 0.93 | POLB (0.40) | TDP1POLBAPEX1HTTTSHR | |
| Styrene SCHEMBL28069493 | 0.92 | POLB (0.39) | TDP1POLBAPEX1HTTTSHR | |
| Styrene SCHEMBL891419 | 0.92 | ALDH1A1 (0.41) | TDP1POLBAPEX1HTTTSHR | |
| Styrene SCHEMBL8361059 | 0.90 | THRB (0.47) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL28116495 | 0.90 | THRB (0.43) | TDP1POLBAPEX1HTTTSHR | |
| Styrene SCHEMBL16753060 | 0.89 | ALDH1A1 (0.39) | TDP1POLBAPEX1HTTTSHR | |
| Styrene SCHEMBL4122830 | 0.89 | TSHR (0.50) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357432-A | COPOLYENE/CONJUGATED/, STYRENE AND A HYDROXY OR GLYCIDYL GROUP | POLYSAR LIMITED (CA) | 1982-11-02 | — | — | US | claimed |
| US-4357432-A | COPOLYENE/CONJUGATED/, STYRENE AND A HYDROXY OR GLYCIDYL GROUP | POLYSAR LIMITED (CA) | 1982-11-02 | — | — | US | disclosed |
| US-4150014-A | HYDROXYL HYDROCARBYL POLYMER, AMINE, SHEARING | POLYSAR LIMITED (CA) | 1979-04-17 | — | — | US | disclosed |