Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313796 | 0.86 | GPR84 (0.37) | CES2CES1PCSK9SIGMAR1 | |
| SCHEMBL27262505 | 0.86 | CSNK1E (0.51) | CSNK1ECNR2MEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL21354368 | 0.86 | CSNK1E (0.48) | CSNK1ECNR2SIGMAR1 | |
| SCHEMBL3816521 | 0.85 | CSNK1E (0.38) | CSNK1ECNR2PRSS1PRSS2PRSS3 | |
| SCHEMBL11245171 | 0.83 | CSNK1E (0.38) | CSNK1ECNR2PRSS1PRSS2PRSS3 | |
| SCHEMBL11242337 | 0.83 | CSNK1E (0.38) | CSNK1ECNR2PRSS1PRSS2PRSS3 | |
| SCHEMBL11240071 | 0.83 | CSNK1E (0.38) | CSNK1ECNR2PRSS1PRSS2PRSS3 | |
| SCHEMBL11237057 | 0.83 | CSNK1E (0.38) | CSNK1ECNR2PRSS1PRSS2PRSS3 | |
| SCHEMBL11249146 | 0.83 | CSNK1E (0.38) | CSNK1ECNR2PRSS1PRSS2PRSS3 | |
| SCHEMBL11233661 | 0.83 | CSNK1E (0.38) | CSNK1ECNR2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087031-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | WO | disclosed |