SCHEMBL11240106

SCHEMBL11240106

ClCc1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.53
HPGD P15428 5/20 0.42
HSD17B10 Q99714 5/20 0.42
TSHR P16473 4/20 0.42
HSP90AA1 P07900 2/20 0.42
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 2/20 0.36
AHR P35869 6/20 0.34
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
CASP1 P29466 1/20 0.33
KMT2A Q03164 2/20 0.31
AKR1B1 P15121 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
USP2 O75604 1/20 0.31
EGFR P00533 1/20 0.31
LMNA P02545 1/20 0.31
ESR1 P03372 1/20 0.31
ERBB2 P04626 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11526199 0.79 CYP3A4 (0.48) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL11560569 0.79
SCHEMBL16860554 0.76 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL7203536 0.76 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL11331781 0.76 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL7203543 0.76 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL7597819 0.76 IDO1 (0.36) CYP3A4ALDH1A1MAPK1AHRKMT2A
SCHEMBL14059607 0.75 CYP3A4 (0.43) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL28493952 0.74 CYP3A4 (0.48) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL3727971 0.72 CYP3A4 (0.42) CYP3A4MAPK1AHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4000052-A METHOD OF PREPARING METHYLCHLOROMETHYLTETRACHLOROBENZENES AND DI-(CHLOROMETHYL)-TETRACHLOROBENZENES DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-12-28 US claimed
CN-111620760-B Method for preparing 2,3,5, 6-tetrachlorobenzonitrile 中南民族大学 2022-05-24 CN disclosed
CN-111620760-A Method for preparing 2,3,5, 6-tetrachlorobenzonitrile, special catalyst and preparation method 中南民族大学 2020-09-04 CN disclosed
CN-100486944-C Novel method for preparing 1-hexene in presence of ethylene oligomerization catalyst system PETROCHINA CO LTD (CN) 2009-05-13 CN disclosed
CN-1203034-C Method for preparing 1-hexene in presence of ethylene oligomerization catalyst system CHINA NAT PETROLEUM CORP (CN) 2005-05-25 CN disclosed
CN-1490291-A Method for preparing 1-hexene in presence of ethylene oligomerization catalyst system 中国石油天然气股份有限公司 2004-04-21 CN disclosed
CN-1490290-A Novel method for preparing 1-hexene in presence of ethylene oligomerization catalyst system 中国石油天然气股份有限公司 2004-04-21 CN disclosed
CN-1128776-C Catalyst for preparing 1-hexene from ethene by oligomerization and its application RES INST OF DAQING PETROCHEMIC (CN) 2003-11-26 CN disclosed
CN-1294109-A Catalyst for preparing 1-hexene from ethene by oligomerization and its application RES INST OPF DAQING PETRO CHEM (CN) 2001-05-09 CN disclosed
US-4331821-A ULTRAVIOLET RADIATION OF A VAPORIZED ALKYLBENZEN AND HALOGEN GAS MIXTURE BAYER AKTIENGESELLSCHAFT (DE) 1982-05-25 US disclosed
US-4283565-A REACTING A BENZYL HALIDE WITH A FORMATE, CONTACTING WITH AN ALCOHOL TO TRANSESTERIFY DYNAMIT NOBEL AG (DE) 1981-08-11 US disclosed
US-4191711-A Process for the preparation of certain nuclear chlorinated benzotrichlorides BAYER AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed
US-4038409-A FUNGICIDES, BACTERICIDES, PROTOZOICIDES SYNTEX (U.S.A.) INC. (US) 1977-07-26 US disclosed
US-4000052-A METHOD OF PREPARING METHYLCHLOROMETHYLTETRACHLOROBENZENES AND DI-(CHLOROMETHYL)-TETRACHLOROBENZENES DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed
US-4000052-A METHOD OF PREPARING METHYLCHLOROMETHYLTETRACHLOROBENZENES AND DI-(CHLOROMETHYL)-TETRACHLOROBENZENES DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed