SCHEMBL7203536

SCHEMBL7203536

[SiH3]Cc1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.50
HPGD P15428 5/20 0.40
HSD17B10 Q99714 5/20 0.40
TSHR P16473 4/20 0.40
HSP90AA1 P07900 2/20 0.40
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 2/20 0.35
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
USP2 O75604 1/20 0.34
EGFR P00533 1/20 0.34
LMNA P02545 1/20 0.34
ESR1 P03372 1/20 0.34
ERBB2 P04626 1/20 0.34
CYP1A2 P05177 1/20 0.34
LCK P06239 1/20 0.34
FYN P06241 1/20 0.34
PGR P06401 1/20 0.34
POLB P06746 1/20 0.34
HTR1A P08908 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17552706 0.77 ALDH1A1 (0.52) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL11240106 0.76 CYP3A4 (0.53) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL16860554 0.74 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL11331781 0.74 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL17552708 0.74 CYP3A4 (0.40) CYP3A4MAPK1AHR
SCHEMBL7203543 0.74 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL17552704 0.72 MAPK1 (0.38) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL11526199 0.72 CYP3A4 (0.48) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL28493952 0.72 CYP3A4 (0.48) CYP3A4HPGDHSD17B10TSHRHSP90AA1
SCHEMBL28008383 0.70 CYP3A4 (0.46) CYP3A4HPGDHSD17B10TSHRHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0763001-B1 SELECTIVE PRODUCTION OF PARA-DIALKYL SUBSTITUTED BENZENES MOBIL OIL CORP (US) 1999-09-08 EP claimed
EP-0128721-B1 SILICA-MODIFIED CATALYST AND USE FOR SELECTIVE PRODUCTION OF PARA-DIALKYL SUBSTITUTED BENZENES MOBIL OIL CORPORATION (US) 1989-07-26 EP claimed
WO-2023204947-A1 PROCESSES FOR OXIDIZING P-XYLENE OR P-XYLENE-CONTAINING MIXTURES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-10-26 WO disclosed
US-6541408-B2 Progressive temperature gradient stabilizes hydrorefining catalysts (metal-modified zeolite) to allow long duration of use and low by-product make EXXONMOBIL OIL CORP. 2003-04-01 US disclosed
US-20020091293-A1 Zeolite catalysts having stabilized hydrogenation-dehydrogenation function EXXONMOBIL OIL CORPORATION 2002-07-11 US disclosed
US-6346498-B1 PERMEATING METAL INTO MOLECULAR SIEVE; IN SITU SELECTIVATION WITH SILICON COMPOUND AND ROASTING; BY-PRODUCT INHIBITION EXXONMOBIL OIL CORPORATION 2002-02-12 US disclosed
US-20010051754-A1 PLURAL STAGE TOLUENE DISPROPORTIONATION PROCESS MINIMIZING ETHYLBENZENE MOBIL OIL CORPORATION 2001-12-13 US disclosed
US-6207871-B1 CONVERTING A HYDROCARBON FEEDSTREAM COMPRISING ETHYLBENZENE AND META-XYLENE OVER MOLECULAR SIEVE CATALYST UNDER ETHYLBENZENE CONVERSION CONDITIONS, MOBIL OIL CORPORATION 2001-03-27 US disclosed
WO-2001009067-A1 PLURAL STAGE TOLUENE DISPROPORTIONATION PROCESS MINIMIZING ETHYLBENZENE PRODUCTION MOBIL OIL CORPORATION (US) 2001-02-08 WO disclosed
US-4532368-A Passing mixture of phenol, ortho-alkylphenol, alkylating agent through zeolite catalyst, separating and recycling ortho-alkylphenols ETHYL CORPORATION (US) 1985-07-30 US disclosed
US-4421941-A OXIDES OF SILICON AND PHOSPHORUS ON A ZEOLITE MOBIL OIL CORPORATION (US) 1983-12-20 US disclosed
US-4379761-A ZEOLITE ALKYLATION CATALYSTS MOBIL OIL CORPORATION (US) 1983-04-12 US disclosed
US-4283306-A CATALYTIC METHYLATION OF TOLUENE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091293-A1 Zeolite catalysts having stabilized hydrogenation-dehydrogenation function HDHD5, HSF1, HRH4 CYP3A4 62/4885HPGD 127/4885HSD17B10 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.