Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262605 | 0.94 | HMOX1 (0.57) | HMOX1CYP1A2CYP3A4CYP2D6CYP11B1 | |
| Bromide SCHEMBL11240418 | 0.93 | HMOX1 (0.56) | HMOX1CYP1A2CYP3A4CYP2D6CYP11B1 | |
| SCHEMBL11238359 | 0.87 | HMOX1 (0.56) | HMOX1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11231971 | 0.87 | CYP19A1 (0.47) | HMOX1CYP1A2CYP3A4CYP2D6CYP11B1 | |
| SCHEMBL11248299 | 0.87 | HMOX1 (0.53) | HMOX1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL443911 | 0.87 | HMOX1 (0.70) | HMOX1 | |
| Hydrochloric Acid SCHEMBL11239982 | 0.86 | HMOX1 (0.70) | HMOX1 | |
| Bromide SCHEMBL11237225 | 0.86 | HMOX1 (0.52) | HMOX1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11240478 | 0.85 | CYP11B1 (0.55) | HMOX1CYP1A2CYP3A4CYP2D6CYP11B1 | |
| SCHEMBL11245231 | 0.85 | CYP19A1 (0.45) | HMOX1CYP1A2CYP3A4CYP2D6CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |