Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.55 |
| ▸ | HMOX1 | P09601 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244436 | 0.95 | CYP11B1 (0.58) | CYP11B1CYP11B2HMOX1KMT2ACYP1A2 | |
| SCHEMBL11250794 | 0.89 | CYP11B1 (0.53) | CYP11B1CYP11B2HMOX1KMT2ACYP1A2 | |
| SCHEMBL11246512 | 0.89 | HMOX1 (0.58) | CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11246782 | 0.88 | CYP11B1 (0.51) | CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11242420 | 0.87 | CYP11B1 (0.54) | CYP11B1CYP11B2HMOX1KMT2ACYP1A2 | |
| SCHEMBL11248299 | 0.85 | HMOX1 (0.53) | CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11239983 | 0.85 | HMOX1 (0.44) | CYP11B1CYP11B2HMOX1IDO1 | |
| SCHEMBL11248555 | 0.85 | CYP11B1 (0.52) | CYP11B1CYP11B2HMOX1KMT2ACYP1A2 | |
| SCHEMBL11240247 | 0.85 | HMOX1 (0.52) | CYP11B1CYP11B2HMOX1CYP1A2CYP3A4 | |
| Bromide SCHEMBL11237225 | 0.84 | HMOX1 (0.52) | CYP11B1CYP11B2HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |