Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984276 | 1.00 | VNN1 (0.43) | VNN1ALDH1A1LMNACHRNA1CHRNG | |
| SCHEMBL994596 | 0.84 | AKR1C1 (0.48) | ALDH1A1LMNAMEN1KMT2AAKR1C1 | |
| SCHEMBL435512 | 0.84 | AKR1C1 (0.48) | ALDH1A1LMNAMEN1KMT2AAKR1C1 | |
| SCHEMBL10659448 | 0.84 | AKR1C1 (0.48) | ALDH1A1LMNAMEN1KMT2AAKR1C1 | |
| Hydrochloric Acid SCHEMBL8114401 | 0.82 | AKR1C1 (0.47) | ALDH1A1LMNAMEN1KMT2AAKR1C1 | |
| Hydrochloric Acid SCHEMBL8114403 | 0.82 | AKR1C1 (0.47) | ALDH1A1LMNAMEN1KMT2AAKR1C1 | |
| SCHEMBL16057460 | 0.79 | AKR1C1 (0.52) | LMNAMEN1KMT2AAKR1C1 | |
| SCHEMBL10981712 | 0.76 | OPRM1 (0.41) | AKR1C1 | |
| SCHEMBL11241224 | 0.75 | AKR1C1 (0.40) | ALDH1A1AKR1C1 | |
| SCHEMBL10992620 | 0.75 | HDAC3 (0.40) | ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316905-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |