Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245753 | 0.85 | MAPT (0.63) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11233436 | 0.83 | KMT2A (0.55) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL2827099 | 0.82 | ALDH1A1 (0.66) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL260606 | 0.82 | KMT2A (0.64) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11246229 | 0.80 | MAPT (0.55) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11238983 | 0.78 | MAPT (0.71) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL7843735 | 0.77 | KMT2A (0.58) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL628112 | 0.77 | PTPRF (0.59) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL6004969 | 0.77 | KCNQ3 (0.51) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11253249 | 0.76 | TRPV1 (0.64) | MAPTALDH1A1KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |