Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GPX4 | P36969 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236072 | 0.88 | HTT (0.39) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| Water SCHEMBL11240458 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9APAX8JAK2 | |
| Water SCHEMBL11240451 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9APAX8JAK2 | |
| SCHEMBL11227688 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2GAACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11235371 | 0.75 | ALDH1A1 (0.47) | NPC1RAB9APAX8MEN1KMT2A | |
| SCHEMBL11230871 | 0.73 | CYP4F2 (0.39) | SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11229519 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6074707 | 0.71 | ADRB2 (0.41) | SMN1; SMN2NPC1RAB9APAX8JAK2 | |
| SCHEMBL11229858 | 0.68 | SMN1; SMN2 (0.33) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31318741 | 0.68 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361579-A | TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0025965-A2 | Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |