SCHEMBL11240770

SCHEMBL11240770

Cc1c([N+](=O)[O-])ncn1C(=NO)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 5/20 0.36
GAA P10253 3/20 0.36
MAPT P10636 8/20 0.35
LMNA P02545 6/20 0.35
HTT P42858 5/20 0.35
RAB9A P51151 1/20 0.35
NLRP1 Q9C000 1/20 0.35
KMT2A Q03164 2/20 0.35
ATM Q13315 1/20 0.34
CYP2C19 P33261 2/20 0.33
THRB P10828 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C9 P11712 1/20 0.33
GFER P55789 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240765 1.00 KDM4E (0.37) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL11238219 0.73 KMT2A (0.43) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL11238223 0.73 KMT2A (0.43) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL11267567 0.71 GAA (0.39) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL11267564 0.71 GAA (0.39) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL11243718 0.69 L3MBTL1 (0.35) ALDH1A1KMT2AL3MBTL1
SCHEMBL11243719 0.69 L3MBTL1 (0.35) ALDH1A1KMT2AL3MBTL1
SCHEMBL11503076 0.68 KDM4E (0.33) KDM4EALDH1A1GAAMAPTATM
SCHEMBL11502993 0.68 KDM4E (0.35) KDM4EALDH1A1GAAMAPTLMNA
SCHEMBL11268333 0.68 ALDH1A1 (0.40) KDM4EALDH1A1GAAMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed