Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336766 | 0.85 | GABRA1 (0.63) | GABRA1GABRB2POLBCNR2ALOX5 | |
| SCHEMBL9196560 | 0.81 | AKR1B1 (0.60) | GABRA1GABRB2POLBCNR2ALOX5 | |
| 2-Allylphenol SCHEMBL29078073 | 0.78 | GABRA1 (0.54) | GABRA1GABRB2POLBCNR2ALOX5 | |
| SCHEMBL4460397 | 0.78 | GABRA1 (0.54) | GABRA1GABRB2POLBCNR2ALOX5 | |
| SCHEMBL4459146 | 0.77 | KLF10 (0.50) | MCL1ALDH1A1KDM4E | |
| SCHEMBL27295914 | 0.77 | MCL1 (0.53) | GABRA1GABRB2POLBMEN1MAPT | |
| SCHEMBL21363203 | 0.76 | MCL1 (0.45) | POLBMAPTAKR1B1MCL1ALDH1A1 | |
| SCHEMBL10454550 | 0.76 | GABRA1 (0.47) | GABRA1GABRB2POLBCNR2ALOX5 | |
| SCHEMBL29394182 | 0.76 | GABRA1 (0.66) | GABRA1GABRB2POLBCNR2ALOX5 | |
| SCHEMBL3821503 | 0.76 | GABRA1 (0.66) | GABRA1GABRB2POLBCNR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329365-A | DIPHENYL ETHERS | BURROUGHS WELLCOME CO. (US) | 1982-05-11 | — | — | US | disclosed |