Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | STK4 | Q13043 | 1/20 | 0.33 |
| ▸ | STK3 | Q13188 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240811 | 0.80 | MAPT (0.35) | MAPTTHRBTP53POLBLMNA | |
| SCHEMBL29430021 | 0.77 | CYP3A4 (0.42) | MAPTTP53LMNAALDH1A1KDM4E | |
| SCHEMBL28284 | 0.77 | CYP3A4 (0.42) | MAPTTP53LMNAALDH1A1KDM4E | |
| SCHEMBL30444451 | 0.77 | CYP3A4 (0.42) | MAPTTP53LMNAALDH1A1KDM4E | |
| SCHEMBL11240578 | 0.75 | CYP3A4 (0.36) | MAPTLMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL7483791 | 0.75 | CYP3A4 (0.39) | MAPTLMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL9255478 | 0.74 | CYP3A4 (0.39) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL9186497 | 0.74 | ALDH1A1 (0.41) | MAPTTP53LMNAALDH1A1KDM4E | |
| SCHEMBL9183030 | 0.74 | CYP3A4 (0.39) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL11967217 | 0.74 | CYP3A4 (0.39) | MAPTTHRBTP53LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |