Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995009 | 0.80 | AKR1C3 (0.31) | — | |
| SCHEMBL1940072 | 0.79 | PTGS2 (0.37) | GPR84PTGS2ESR1TP53CYP3A4 | |
| SCHEMBL5685256 | 0.78 | MEN1 (0.32) | SLC6A4MEN1KMT2A | |
| SCHEMBL283991 | 0.77 | PTGS2 (0.44) | PTGS2ESR1TP53CYP3A4ADRA2A | |
| SCHEMBL1778766 | 0.77 | PTGS2 (0.36) | GPR84PTGS2ESR1TP53CYP3A4 | |
| SCHEMBL827972 | 0.77 | PTGS2 (0.44) | PTGS2ESR1TP53CYP3A4ADRA2A | |
| SCHEMBL8574350 | 0.77 | PTGS2 (0.36) | GPR84PTGS2ESR1TP53CYP3A4 | |
| SCHEMBL1778966 | 0.77 | PTGS2 (0.44) | PTGS2ESR1TP53CYP3A4ADRA2A | |
| SCHEMBL8709834 | 0.77 | PTGS2 (0.36) | GPR84PTGS2ESR1TP53CYP3A4 | |
| SCHEMBL7646225 | 0.77 | PTGS2 (0.36) | GPR84PTGS2ESR1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016665-B1 | PROCESS FOR THE PREPARATION OF XANTHONE DERIVATIVES | ROUSSEL-UCLAF (FR) | 1982-05-05 | — | — | EP | disclosed |
| EP-0016665-A1 | Process for the preparation of xanthone derivatives | ROUSSEL-UCLAF (FR) | 1980-10-01 | — | — | EP | disclosed |