SCHEMBL827972

SCHEMBL827972

CCCCCCCCCc1[c]ccc(CCCCCCCCC)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.44
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
CYP3A4 P08684 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
SHBG P04278 1/20 0.44
TP53 P04637 1/20 0.44
HSPD1 P10809 1/20 0.44
ADRB3 P13945 1/20 0.44
HTR2C P28335 1/20 0.44
HSPE1 P61604 1/20 0.44
HIF1A Q16665 1/20 0.44
TST Q16762 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1778966 1.00 PTGS2 (0.44) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL283991 1.00 PTGS2 (0.44) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2089194 1.00 PTGS2 (0.44) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1777578 0.98 PTGS2 (0.43) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL677464 0.98 PTGS2 (0.42) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL22264051 0.96 PTGS2 (0.41) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1776240 0.95 LPL (0.39) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL11039260 0.93 PTGS2 (0.44) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL15610595 0.93 LPL (0.38) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL677715 0.92 SKP2 (0.43) PTGS2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778776-A1 SELF-EMULSIFYING LIQUID STABILISERS Chemtura Europe GmbH (CH) 2007-05-02 EP claimed
WO-2006018597-A1 SELF-EMULSIFYING LIQUID STABILISERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2006-02-23 WO claimed
CN-1148404-C Stabilization of silicone elastomer molds �޵��ǻ�ѧ��˾ 2004-05-05 CN claimed
EP-1299455-A1 STABILISING POLYMERIC, ORGANOSILICON OR SILICONE COMPOSITIONS RHODIA CHIMIE (FR) 2003-04-09 EP claimed
WO-2002006381-A1 STABILISING POLYMERIC, ORGANOSILICON OR SILICONE COMPOSITIONS RHODIA CHIMIE (FR) 2002-01-24 WO claimed
US-4649102-A HYDROPHILIC COLLOID CONTAINING NONIONIC AND ANIONIC SURFACTANTS, ANTISTATIC FUJI PHOTO FILM CO., LTD. (JP) 1987-03-10 US claimed
US-4624913-A POLYOXYETHYLENE SURFACTANT, MESO-IONIC TRIAZOLIUM COMPOUND, DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 1986-11-25 US claimed
CN-114381061-B Polyethylene resin composition and method for producing the same 韩华道达尔能源有限公司 2023-09-12 CN disclosed
CN-116396549-A Polyethylene resin composition, method for producing the same, and molded article comprising the same 韩华道达尔能源有限公司 2023-07-07 CN disclosed
CN-114381061-A Polyethylene resin composition and method for producing the same 韩华道达尔有限公司 2022-04-22 CN disclosed
CN-106380729-B Novel PVC heat stabilizer 邵卫东 2019-01-29 CN disclosed
CN-106380729-A Novel PVC heat stablizer 邵卫东 2017-02-08 CN disclosed
US-9238726-B2 Molded article comprising polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-01-19 US disclosed
EP-0155912-A2 Radiation-stabilized polymer compositions CIBA-GEIGY AG (CH) 1985-09-25 EP disclosed
US-4461641-A CHLOROTRIAZINES, CHLOROACETANILIDES, SURFACTANTS AND WATER CIBA-GEIGY CORPORATION (US) 1984-07-24 US disclosed
EP-0001284-B1 UV-LIGHT STABILIZED COMPOSITIONS CONTAINING SUBSTITUTED 2-KETO-1,4-DIAZACYCLOALKANES The B.F. GOODRICH Company (US) 1984-05-23 EP disclosed
EP-0030310-B1 INTERNAL RELEASE AGENT FOR HEAT-CURABLE AMINOPLAST RESINS, PROCESS FOR ITS PRODUCTION AND ITS USE CASSELLA Aktiengesellschaft (DE) 1984-03-28 EP disclosed
EP-0088049-A1 Herbicidal mixtures CIBA-GEIGY AG (CH) 1983-09-07 EP disclosed
US-4310355-A DISPERSION OF A PHOSPHATE SALT AND A CARBOXYLIC ACID SALT OR A SULFONATE SALT CASSELLA AKTIENGESELLSCHAFT (DE) 1982-01-12 US disclosed
EP-0030310-A1 Internal release agent for heat-curable aminoplast resins, process for its production and its use CASSELLA Aktiengesellschaft (DE) 1981-06-17 EP disclosed