Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241126 | 0.90 | TDP1 (0.81) | TDP1RORCGCGRRAB9ANPC1 | |
| SCHEMBL11242279 | 0.88 | TDP1 (0.61) | TDP1GCGRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11385942 | 0.88 | GCGR (0.62) | TDP1GCGRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11243370 | 0.88 | GCGR (0.62) | TDP1GCGRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11250867 | 0.88 | TDP1 (0.63) | TDP1GCGRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11385899 | 0.88 | TDP1 (0.60) | TDP1GCGRRAB9ANPC1SMN1; SMN2 | |
| Chlotrifmeuron SCHEMBL10868747 | 0.87 | TDP1 (0.70) | TDP1RORCGCGRRAB9ANPC1 | |
| SCHEMBL11235155 | 0.86 | RAB9A (0.63) | TDP1GCGRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11236585 | 0.86 | TDP1 (0.58) | TDP1GCGRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11236840 | 0.84 | LRRK2 (0.50) | TDP1GCGRRAB9ANPC1PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |