Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 12/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239700 | 0.85 | AOC3 (0.42) | SMN1; SMN2KMT2AAOC3LMNANPC1 | |
| SCHEMBL9817424 | 0.84 | HRH2 (0.40) | SMN1; SMN2KMT2AAOC3MAOBSLC22A2 | |
| SCHEMBL11239873 | 0.82 | AOC3 (0.47) | SMN1; SMN2KMT2AAOC3MAOB | |
| SCHEMBL10744734 | 0.82 | ABL1 (0.42) | SMN1; SMN2KMT2AAOC3SLC22A2CA12 | |
| SCHEMBL10587291 | 0.81 | HRH2 (0.39) | SMN1; SMN2KMT2AAOC3MAOBSLC22A2 | |
| Hydrochloric Acid SCHEMBL11237444 | 0.81 | AOC3 (0.39) | SMN1; SMN2KMT2AAOC3MAOBSLC22A2 | |
| SCHEMBL10585196 | 0.81 | SLC22A2 (0.41) | SMN1; SMN2KMT2AAOC3MAOBSLC22A2 | |
| SCHEMBL11250612 | 0.81 | PDE5A (0.44) | SMN1; SMN2KMT2ASLC22A2CA12SLC22A3 | |
| SCHEMBL10743849 | 0.81 | CDK5 (0.40) | SMN1; SMN2KMT2AAOC3SLC22A2CA12 | |
| Hydrochloric Acid SCHEMBL10439042 | 0.80 | HRH2 (0.39) | SMN1; SMN2KMT2AAOC3MAOBSLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362736-A | ANTISECRETORY AGENTS, GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |