Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.42 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241210 | 0.85 | SMN1; SMN2 (0.39) | AOC3CDK5CDK5R1NPC1RAB9A | |
| SCHEMBL11241379 | 0.82 | LMNA (0.36) | AOC3PDE5AKDM4EALDH1A1NPC1 | |
| SCHEMBL9817424 | 0.80 | HRH2 (0.40) | AOC3PDE5AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11388323 | 0.78 | ALDH1A1 (0.40) | PDE5AKDM4ECDK5CDK5R1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10439042 | 0.78 | HRH2 (0.39) | AOC3PDE5ACDK5CDK5R1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11236238 | 0.78 | HRH2 (0.39) | AOC3PDE5ACDK5CDK5R1ALDH1A1 | |
| SCHEMBL10587291 | 0.77 | HRH2 (0.39) | AOC3PDE5ACDK5CDK5R1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11249076 | 0.77 | SLC22A2 (0.37) | AOC3PDE5AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11237444 | 0.77 | AOC3 (0.39) | AOC3PDE5AKDM4ECDK5CDK5R1 | |
| SCHEMBL10743849 | 0.77 | CDK5 (0.40) | AOC3PDE5ACDK5CDK5R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362736-A | ANTISECRETORY AGENTS, GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |