Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11241263 | 0.81 | PTGS2 (0.51) | PTGS2FFAR1GRIA4GAA | |
| SCHEMBL11134856 | 0.79 | PTGS2 (0.56) | PTGS2FFAR1GRIA4MEN1KMT2A | |
| SCHEMBL21237780 | 0.77 | FFAR1 (0.67) | PTGS2FFAR1GRIA4MMP12GAA | |
| SCHEMBL7858991 | 0.77 | FFAR1 (0.67) | PTGS2FFAR1GRIA4MMP12GAA | |
| SCHEMBL27901034 | 0.74 | LTB4R (0.47) | FFAR1CYP2C19 | |
| SCHEMBL21237726 | 0.74 | PTGS2 (0.55) | PTGS2FFAR1GRIA4MEN1KMT2A | |
| SCHEMBL21237722 | 0.74 | PTGS2 (0.55) | PTGS2FFAR1GRIA4MEN1KMT2A | |
| SCHEMBL11489425 | 0.74 | PTGS2 (0.55) | PTGS2FFAR1GRIA4GAA | |
| SCHEMBL13140340 | 0.73 | FFAR1 (0.56) | PTGS2FFAR1MMP12ACACBACACA | |
| SCHEMBL27841756 | 0.72 | HPGD (0.44) | FFAR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344966-A | Anti-inflammatory 1-alkyl-1-phenyl-butanes | SANDOZ, INC. (US) | 1982-08-17 | — | — | US | disclosed |
| US-4081476-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1978-03-28 | — | — | US | disclosed |