Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239909 | 0.98 | MMP2 (0.41) | LIPACA12CA1CA2MMP1 | |
| SCHEMBL11253300 | 0.83 | HPGD (0.41) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL11240530 | 0.81 | HPGD (0.43) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL11242725 | 0.81 | HPGD (0.43) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL11241149 | 0.79 | CYP1A2 (0.41) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL9662429 | 0.77 | LIPA (0.44) | LIPAKMT2AHPGDEPHX1SMN1; SMN2 | |
| SCHEMBL8242270 | 0.75 | HPGD (0.45) | LIPAKMT2AHPGDEPHX1NPC1 | |
| SCHEMBL11241635 | 0.74 | LIPA (0.33) | LIPAMETAP1HPGDFDPS | |
| SCHEMBL12208661 | 0.73 | LIPA (0.44) | LIPAKMT2AHPGDEPHX1SMN1; SMN2 | |
| SCHEMBL11244276 | 0.72 | CA12 (0.38) | CA12CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361577-A | ANTIULCER AND LUTEOLYTIC AGENTS | CARLO ERBA - S.P.A. (IT) | 1982-11-30 | — | — | US | disclosed |
| US-4169145-A | ANTIULCER AGENTS, LUTEOLYTIC ABORTIFACIENTS, OXYTOCICS | CARLO ERBA S.P.A. (IT) | 1979-09-25 | — | — | US | disclosed |
| US-4035415-A | GASTROINTESTINAL DISORDERS | CARLO ERBA, S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |