Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242725 | 1.00 | HPGD (0.43) | HPGDMETAP1HSD11B1CA12CA1 | |
| SCHEMBL11253300 | 0.98 | HPGD (0.41) | HPGDMETAP1HSD11B1CA12CA1 | |
| SCHEMBL11241635 | 0.91 | LIPA (0.33) | HPGDMETAP1HSD11B1MAPT | |
| SCHEMBL11241149 | 0.90 | CYP1A2 (0.41) | HPGDMETAP1HSD11B1CA12CA1 | |
| SCHEMBL11239909 | 0.84 | MMP2 (0.41) | HPGDMETAP1CA12CA1CA2 | |
| SCHEMBL11241408 | 0.81 | LIPA (0.39) | HPGDMETAP1CA12CA1CA2 | |
| SCHEMBL4178019 | 0.79 | HPGD (0.50) | HPGDHSD11B1ATMMEN1MAPT | |
| SCHEMBL13543224 | 0.77 | HPGD (0.47) | HPGDHSD11B1ATMMEN1MAPT | |
| SCHEMBL12378313 | 0.74 | HSD11B1 (0.46) | HPGDHSD11B1ATMMEN1MAPT | |
| SCHEMBL10709268 | 0.73 | HPGD (0.44) | HPGDHSD11B1ATMMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361577-A | ANTIULCER AND LUTEOLYTIC AGENTS | CARLO ERBA - S.P.A. (IT) | 1982-11-30 | — | — | US | disclosed |
| US-4169145-A | ANTIULCER AGENTS, LUTEOLYTIC ABORTIFACIENTS, OXYTOCICS | CARLO ERBA S.P.A. (IT) | 1979-09-25 | — | — | US | disclosed |
| US-4035415-A | GASTROINTESTINAL DISORDERS | CARLO ERBA, S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |