SCHEMBL11241471

SCHEMBL11241471

O=C(NC(=O)c1ccccc1Cl)Nc1cc(Cl)c(OCc2ccc(Cl)cc2)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGL P06737 7/20 0.64
GCGR P47871 1/20 0.58
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
PNLIP P16233 1/20 0.46
PLCG2 P16885 1/20 0.45
PCTP Q9UKL6 1/20 0.44
SENP5 Q96HI0 1/20 0.44
SENP2 Q9HC62 1/20 0.44
SENP1 Q9P0U3 1/20 0.44
MAPT P10636 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
SMO Q99835 2/20 0.43
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11243077 0.93 PYGL (0.69) PYGLGCGRNPC1RAB9APOLB
SCHEMBL11240053 0.90 PYGL (0.53) PYGLGCGRNPC1RAB9APOLB
SCHEMBL11240584 0.88 PYGL (0.58) PYGLGCGRNPC1RAB9APOLB
SCHEMBL11246588 0.87 PYGL (0.57) PYGLGCGRNPC1RAB9APOLB
SCHEMBL11237411 0.87 GCGR (0.71) PYGLGCGRNPC1RAB9APOLB
SCHEMBL11385942 0.85 GCGR (0.62) PYGLGCGRNPC1RAB9APOLB
SCHEMBL11243370 0.85 GCGR (0.62) PYGLGCGRNPC1RAB9APOLB
SCHEMBL8662510 0.83 PYGL (0.57) PYGLGCGRNPC1RAB9APOLB
SCHEMBL9683671 0.82 GCGR (0.75) PYGLGCGRNPC1RAB9APOLB
SCHEMBL11230531 0.82 MAPT (0.47) PYGLGCGRNPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4350706-A MITICIDES, LARVICIDES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1982-09-21 US disclosed